New high-purity porous spherical silica chemically bonded with the aminopropyl group ensures the superior stability of Shim-pack GIST NH2. It is capable of the analysis of vitamin E or simultaneous analysis of sugars that are hard to separate in reversed phase mode. In addition, due to being primarily amine-bound, Shim-pack GIST NH2 can analyze sugars with no separation of anomers, even under low-temperature conditions. Furthermore, Shim-pack GIST NH2 delivers highly reliable reproducibility and stability with accurate qualitative and quantitative results.